Peter E Light Selected Research

Non-alcoholic Fatty Liver Disease

1/2019

The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity.

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Peter E Light Research Topics

Disease

13	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2003
7	Ischemia 01/2021 - 01/2005
6	Heart Failure 01/2022 - 01/2013
4	Obesity 01/2019 - 07/2008
4	Hypoxia (Hypoxemia) 07/2012 - 08/2003
3	Insulin Resistance 01/2019 - 06/2010
3	Reperfusion Injury 09/2017 - 03/2004
3	Cardiomegaly (Heart Hypertrophy) 07/2015 - 08/2008
3	Hypertrophy 08/2008 - 05/2006
2	Cardiac Arrhythmias (Arrythmia) 01/2021 - 08/2015
2	Inflammation (Inflammations) 10/2020 - 01/2020
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 08/2008
2	Glucose Intolerance 01/2019 - 02/2017
2	Atrial Fibrillation 08/2015 - 01/2014
1	Hyperlactatemia 10/2022
1	Critical Illness (Critically Ill) 10/2022
1	Long Qt Syndrome 3 01/2021
1	Diabetes Mellitus 01/2020
1	Non-alcoholic Fatty Liver Disease 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Atrial Remodeling 01/2015
1	Cardiomyopathies (Cardiomyopathy) 01/2013
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2013
1	Metabolic Diseases (Metabolic Disease) 06/2010
1	Hyperinsulinism (Hyperinsulinemia) 01/2010
1	Epilepsy (Aura) 01/2010
1	Neoplasms (Cancer) 03/2009
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 03/2009
1	Hypertension (High Blood Pressure) 03/2009
1	Pulmonary Arterial Hypertension 07/2007
1	Left Ventricular Dysfunction 12/2006
1	Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome) 05/2006
1	Insulinoma 04/2003

Drug/Important Bio-Agent (IBA)

9	Adenosine Triphosphate (ATP)IBA 03/2012 - 03/2004
7	CalciumIBA 01/2020 - 06/2005
4	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 07/2010
4	Fatty Acids (Saturated Fatty Acids)IBA 09/2017 - 06/2010
4	ResveratrolIBA 08/2015 - 08/2008
3	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 01/2021
3	Pharmaceutical PreparationsIBA 01/2022 - 01/2005
3	Ranolazine FDA Link 01/2019 - 12/2006
3	Insulin (Novolin)FDA Link 06/2017 - 12/2011
3	AMP-Activated Protein KinasesIBA 07/2015 - 05/2006
3	PotassiumIBA 03/2012 - 03/2004
3	KATP ChannelsIBA 03/2012 - 10/2003
2	Sodium-Glucose Transport ProteinsIBA 01/2022 - 01/2021
2	empagliflozinIBA 01/2021 - 01/2020
2	Sodium Channels (Sodium Channel)IBA 01/2021 - 12/2006
2	InflammasomesIBA 01/2021 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2009
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020 - 12/2002
2	Ion Channels (Ion Channel)IBA 08/2015 - 05/2006
2	LipidsIBA 01/2015 - 06/2010
2	Voltage-Gated Sodium ChannelsIBA 11/2012 - 05/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2011 - 11/2009
2	Phosphotransferases (Kinase)IBA 03/2009 - 08/2008
2	EstersIBA 07/2008 - 03/2004
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2022
1	Tetrodotoxin (Tetradotoxin)IBA 01/2021
1	TRPV Cation ChannelsIBA 10/2020
1	LigandsIBA 10/2020
1	IonophoresIBA 01/2020
1	NucleotidesIBA 01/2020
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	Pyruvic Acid (Pyruvate)IBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 07/2015
1	Biomarkers (Surrogate Marker)IBA 07/2014
1	CalreticulinIBA 01/2013
1	SodiumIBA 11/2012
1	Cardiac GlycosidesIBA 11/2012
1	11,12-epoxy-5,8,14-eicosatrienoic acidIBA 07/2012
1	Sulfonylurea ReceptorsIBA 12/2011
1	3-nitrotyrosineIBA 05/2011
1	Contractile ProteinsIBA 05/2011
1	IronIBA 05/2011
1	NitratesIBA 05/2011
1	NitritesIBA 05/2011
1	PhenanthrolinesIBA 05/2011
1	Myosin Light Chains (Myosin Essential Light Chain)IBA 05/2011
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 05/2011
1	Peroxynitrous Acid (Peroxynitrite)IBA 05/2011
1	Triglycerides (Triacylglycerol)IBA 06/2010
1	2- (2- (4- (4- nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonateIBA 11/2009
1	Gliclazide (Diamicron)IBA 10/2009
1	TOR Serine-Threonine KinasesIBA 03/2009
1	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 03/2009
1	Protein Isoforms (Isoforms)IBA 12/2008
1	CalcineurinIBA 08/2008
1	Phosphodiesterase 5 InhibitorsIBA 07/2007
1	Sildenafil Citrate (Viagra)FDA Link 07/2007
1	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 07/2007
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 02/2007
1	Methazolamide FDA LinkGeneric 02/2007
1	GlycogenIBA 05/2006
1	Hormones (Hormone)IBA 03/2004
1	Acyl Coenzyme A (Acyl CoA)IBA 03/2004
1	Fura-2 (Fura 2)IBA 08/2003
1	WortmanninIBA 04/2003
1	LY 303511IBA 04/2003

Therapy/Procedure

7	Therapeutics 01/2019 - 03/2009